{"product_id":"proteintech-98701-3-rr","title":"Proteintech, 98701-3-RR, Anti-Canine IL-2 Rabbit Recombinant Antibody","description":"Size: 100ug\nThe IL-2 (98701-3-RR) by Proteintech is a Recombinant antibody targeting IL-2 in FC (Intra) applications with reactivity to canine samples\n98701-3-RR targets IL-2 in FC (Intra) applications and shows reactivity with canine samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC (Intra) detected in: Transfected CHO-K1 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nInterleukin-2 (IL-2) is a four-helix bundle, type I cytokine that functions as a growth factor for a wide range of leukocytes. In the immune system, IL-2 is essential for immune homeostasis, normal T regulatory cell function, and self-tolerance. It regulates immune cell homeostasis and has been used to treat a range of disorders including cancer and autoimmune disease. IL-2 signals through heterodimerization of the IL-2Rβ and IL-2Rγ receptor subunits (PMID: 25992858, 24907378, 15034008, 17981641).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: canine\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Eg4556 Product name: Recombinant Canine IL-2 protein (rFc Tag) (HPLC verified) Source: mammalian cells -derived, pHZ-KIsec-N-rFc Tag: N-rFc Domain: 21-155 aa of NM_001003305.1 Sequence: APITSSSTKETEQQMEQLLLDLQLLLNGVNNYENPQLSRMLTFKFYTPKKATEFTHLQCLAEELKNLEEVLGLPQSKNVHLTDTKELISNMNVTLLKLKGSETSYNCEYDDETATITEFLNKWITFCQSIFSTLT Predict reactive species\nFull Name: IL-2\nCalculated Molecular Weight: 18 kDa\nGenBank Accession Number: NM_001003305.1\nGene Symbol: IL-2\nGene ID (NCBI): 403989\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q29416\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2 - 8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888693530793,"sku":"98701-3-RR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-98701-3-rr","provider":"Iright","version":"1.0","type":"link"}