{"product_id":"proteintech-apc-fca65570","title":"Proteintech, APC-FcA65570, FcZero-rAb™ APC Anti-Human CD3 (UCHT1) Rabbit Recombinant Antibody","description":"Size: 100tests\nThe CD3 (APC-FcA65570) by Proteintech is a Recombinant antibody targeting CD3 in FC applications with reactivity to human samples\nAPC-FcA65570 targets CD3 in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 5 ul per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor Predict reactive species\nFull Name: CD3e molecule, epsilon (CD3-TCR complex)\nCalculated Molecular Weight: 207 aa, 23 kDa\nGenBank Accession Number: BC049847\nGene Symbol: CD3\nGene ID (NCBI): 916\nENSEMBL Gene ID: ENSG00000198851\nConjugate: APC Fluorescent Dye\nExcitation\/Emission Maxima Wavelengths: 650 nm \/ 660 nm\nExcitation Laser: Red Laser (633 nm)\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P07766\nStorage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.\nStorage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888617115817,"sku":"APC-FcA65570","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-apc-fca65570","provider":"Iright","version":"1.0","type":"link"}