{"product_id":"proteintech-apc-fca65581","title":"Proteintech, APC-FcA65581, FcZero-rAb™ APC Anti-Human CD83 (HB15e) Rabbit IgG Recombinant Antibody","description":"Size: 100tests\nThe CD83 (APC-FcA65581) by Proteintech is a Recombinant antibody targeting CD83 in FC applications with reactivity to human, non-human primates samples\nAPC-FcA65581 targets CD83 in FC applications and shows reactivity with human, non-human primates samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human monocyte-derived mature dendritic cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 5 ul per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD83 is a member of the immunoglobulin (Ig) superfamily, consisting of an extracellular V-type Ig-like domain, a transmembrane domain, and a cytoplasmic tail. CD83 is one of the most prominent markers for fully matured dendritic cells (DCs) (PMID: 17334966). It is also found on the surface of other activated hematopoietic cells, including lymphocytes, monocytes, macrophages, and neutrophils (PMID: 31231400; 17334966). CD83 regulates the maturation, activation, and homeostasis of numerous immune cells (PMID: 31231400; 32362900). CD83 can also expressed as a soluble form. Soluble CD83 can bind to DCs and inhibit their maturation (PMID: 17334966; 12403928).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, non-human primates\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Human CD83-transfected Cos cells Predict reactive species\nFull Name: CD83 molecule\nCalculated Molecular Weight: 205 aa, 23 kDa\nGenBank Accession Number: BC030830\nGene Symbol: CD83\nGene ID (NCBI): 9308\nENSEMBL Gene ID: ENSG00000112149\nConjugate: APC Fluorescent Dye\nExcitation\/Emission Maxima Wavelengths: 650 nm \/ 660 nm\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q01151\nStorage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.\nStorage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888622620841,"sku":"APC-FcA65581","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-apc-fca65581","provider":"Iright","version":"1.0","type":"link"}