{"product_id":"proteintech-apc-fca65582","title":"Proteintech, APC-FcA65582, FcZero-rAb™ APC Anti-Human CD11b (ICRF44) Rabbit IgG Recombinant Antibody","description":"Size: 100tests\nThe CD11b (APC-FcA65582) by Proteintech is a Recombinant antibody targeting CD11b in FC applications with reactivity to human samples\nAPC-FcA65582 targets CD11b in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 5 ul per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIntegrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α\/β heterodimer with CD18 (integrin β2). CD11b\/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b\/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Rheumatoid synovial cells and human monocytes Predict reactive species\nFull Name: integrin, alpha M (complement component 3 receptor 3 subunit)\nCalculated Molecular Weight: 1152 aa, 127 kDa\nGenBank Accession Number: BC096346\nGene Symbol: CD11b\nGene ID (NCBI): 3684\nENSEMBL Gene ID: ENSG00000169896\nConjugate: APC Fluorescent Dye\nExcitation\/Emission Maxima Wavelengths: 650 nm \/ 660 nm\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P11215\nStorage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.\nStorage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888614854825,"sku":"APC-FcA65582","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-apc-fca65582","provider":"Iright","version":"1.0","type":"link"}