{"product_id":"proteintech-apc-fca98018","title":"Proteintech, APC-FcA98018, FcZero-rAb™ APC Anti-Mouse TLR4\/CD284 Rabbit Recombinant Antibody","description":"Size: 100ug\nThe TLR4\/CD284 (APC-FcA98018) by Proteintech is a Recombinant antibody targeting TLR4\/CD284 in FC applications with reactivity to mouse samples\nAPC-FcA98018 targets TLR4\/CD284 in FC applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: Balb\/c mouse peritoneal macrophages\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.1 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nTLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 interacts with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kB activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: CatNo: Ag32998 Product name: Recombinant mouse Tlr4 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 198-395 aa of NM_021297 Sequence: RENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLG Predict reactive species\nFull Name: toll-like receptor 4\nCalculated Molecular Weight: 96 kDa\nGenBank Accession Number: NM_021297\nGene Symbol: Tlr4\nGene ID (NCBI): 21898\nConjugate: APC Fluorescent Dye\nExcitation\/Emission Maxima Wavelengths: 650 nm \/ 660 nm\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q9QUK6\nStorage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.\nStorage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888871067817,"sku":"APC-FcA98018","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-apc-fca98018","provider":"Iright","version":"1.0","type":"link"}