{"product_id":"proteintech-biotin-sf98190","title":"Proteintech, Biotin-SF98190, Biotin Anti-Human CD98\/SLC3A2 Rabbit scFv Antibody","description":"Size: 100ug\nThe CD98\/SLC3A2 (Biotin-SF98190) by Proteintech is a Recombinant antibody targeting CD98\/SLC3A2 in FC, ELISA applications with reactivity to human samples\nBiotin-SF98190 targets CD98\/SLC3A2 in FC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD98 is a 125-kDa type II membrane glycoprotein heterodimer composed of a 40-kDa non-glycosylated light chain (amino-acid transporter, encoded by the SLC7A5) and an 85-kDa glycosylated heavy chain (CD98hc, encoded by the SLC3A2) (PMID: 11507094). CD98hc also interacts with certain integrin b-subunits to regulate cell migration, survival, proliferation, and adhesion\/polarity. CD98hc is overexpressed on the cell surface of many cancers and increased CD98hc expression is associated with the development and progression of tumors.(PMID:25084765). Molecular orientation studies have demonstrated that the C-terminal tail of human CD98 (hCD98), which contains a PDZ-binding domain, is extracellular (PMID: 18625289).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Type: Rabbit \/ scFv\nClass: Recombinant\nType: Single-chain variable fragment antibody (scFv)\nImmunogen: CatNo: Eg1948 Product name: Recombinant Human CD98\/SLC3A2 protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-N-rFc Tag: N-rFc Domain: 206-630 aa of NM_002394.5 Sequence: RAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAGNLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWFSTQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLLLTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAALPGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQNERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA Predict reactive species\nFull Name: solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2\nCalculated Molecular Weight: 68 kDa\nGenBank Accession Number: NM_002394.5\nGene Symbol: CD98\nGene ID (NCBI): 6520\nConjugate: Biotin\nExcitation\/Emission Maxima Wavelengths: -\nSource: Anti-Human CD98\/SLC3A2 scFv from clone 241755D6, consisting of VH-GGGGS linker-VL (N- to C-terminus), with His tag at the C-terminus.\nForm: Liquid\nPurification Method: Affinity purification\nStorage Buffer: PBS with 4% sucrose and 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888547516585,"sku":"Biotin-SF98190","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-biotin-sf98190","provider":"Iright","version":"1.0","type":"link"}