{"product_id":"proteintech-cl594-84590","title":"Proteintech, CL594-84590, CoraLite®594-conjugated Phospho-CRKL (Tyr207) Recombinant monoclonal antibody","description":"Size: 100ul\nThe Phospho-CRKL (Tyr207) (CL594-84590) by Proteintech is a Recombinant antibody targeting Phospho-CRKL (Tyr207) in FC (Intra) applications with reactivity to human, mouse samples\nCL594-84590 targets Phospho-CRKL (Tyr207) in FC (Intra) applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC (Intra) detected in: λ phosphatase treated K-562 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSimilar to other adaptor proteins, Crk functions primarily to assemble molecular complexes to distribute signals within the cell. The best studied regulatory mechanism of Crk proteins is the phosphorylation at a tyrosine located in a linker between the N- and C-terminal SH3 domains (Tyr221 in human CrkII, Tyr207 in human CrkL). (PMID: 24675776)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Recombinant\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: v-crk sarcoma virus CT10 oncogene homolog (avian)-like\nCalculated Molecular Weight: 34 kDa\nObserved Molecular Weight: 39 kDa\nGenBank Accession Number: BC043500\nGene Symbol: CRKL\nGene ID (NCBI): 1399\nConjugate: CoraLite®594 Fluorescent Dye\nExcitation\/Emission Maxima Wavelengths: 588 nm \/ 604 nm\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P46109\nStorage Buffer: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.\nStorage Conditions: Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888800485545,"sku":"CL594-84590","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-cl594-84590","provider":"Iright","version":"1.0","type":"link"}