Agilent, 5190-2405, Agilent Bio MAb, NP5, 4.6 x 250 mm

Agilent Bio MAb, NP5, 4.6 x 250 mm. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. The particles are nonporous and promote higher resolution and faster separations.

Specifications:
Brand: Agilent Bio MAb
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 250 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: Charge Variant AnalysisPeptidesProteinsmAbs
Particle Size: 5 µm
Particle Type: Non-porous
Phase: WCX
Pressure Rating: 413 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-12

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Designed for superior performance in monoclonal antibody characterization and analysis, this high-quality column features a 4.6 mm by 250 mm dimension and incorporates non-porous 5-micron particles to ensure excellent resolution during biomolecule separations. Its robust construction supports optimal separation of intact antibodies, fragments, and related variants, making it ideal for critical quality attribute assessment in biopharmaceutical workflows.

Researchers benefit from consistent peak shapes and reproducible results in hydrophobic interaction chromatography and aggregate analysis, enhancing accuracy in method development and routine QC testing. The column is compatible with leading liquid chromatography platforms, including Agilent InfinityLab and 1100, 1200, or 1290 series LC systems, ensuring seamless integration into existing laboratory setups.

Suited for applications such as clone screening, process development, and lot-to-lot consistency studies, this column simplifies monitoring of molecular integrity and product heterogeneity in therapeutic antibody production. It is also an excellent match for other Agilent Bio MAb columns or consumables used in antibody purification and analytical workflows. Overall, this column streamlines monoclonal antibody analysis with reliable performance, high throughput capability, and durability for repeated usage in demanding research and quality assurance environments.