Agilent, 5190-2407, Agilent Bio MAb, NP5, 4.6 x 250 mm, PEEK

Agilent Bio MAb, NP5, 4.6 x 250 mm, PEEK. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. PEEK hardware enables this column to couple with bio-compatible or bio-inert LC systems.

Specifications:
Brand: Agilent Bio MAb
Hardware: PEEK
Inner Diameter (ID): 4.6 mm
LC Platform: BioInert
Length: 250 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: Charge Variant AnalysisPeptidesProteinsmAbs
Particle Size: 5 µm
Particle Type: Non-porous
Phase: WCX
Pressure Rating: 413 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-12

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The Agilent Bio MAb NP5 4.6 x 250 mm PEEK column is engineered for high-performance analysis and characterization of monoclonal antibodies in pharmaceutical and biotherapeutic research. Designed with advanced non-porous NP5 resin and precision PEEK hardware, this column delivers exceptional resolution, reproducibility, and fast separations for complex protein samples. It is ideal for size exclusion chromatography methods, aggregate analysis, and purity assessments of therapeutic antibodies during development, quality control, and lot release processes.

The column supports a wide range of buffer systems and is fully compatible with leading HPLC and UHPLC platforms, including Agilent 1100, 1200, and 1260 Infinity Series systems. Its robust construction ensures excellent longevity and resistance to typical bioanalytical solvents, minimizing carryover and maintaining accurate results across extended analyses. The column is especially suited for laboratories performing routine characterization, stability studies, or comparability assessments of monoclonal antibodies and related biomolecules.

For optimized workflow, this column can be used alongside Agilent Bio HPLC standards and detection solutions, ensuring reliable and reproducible data. Researchers benefit from high-throughput capability, precise size-based separation, and consistent batch-to-batch performance, making it a trusted choice for biopharmaceutical analytical needs.