Agilent, 5190-2420, Agilent Bio MAb, NP10, 2.1 x 50 mm, PEEK

Agilent Bio MAb, NP10, 2.1 x 50 mm, PEEK. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. PEEK hardware enables this column to couple with bio-compatible or bio-inert LC systems.

Specifications:
Brand: Agilent Bio MAb
Hardware: PEEK
Inner Diameter (ID): 2.1 mm
LC Platform: BioInert
Length: 50 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: Charge Variant AnalysisPeptidesProteinsmAbs
Particle Size: 10 µm
Particle Type: Non-porous
Phase: WCX
Pressure Rating: 275 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-12

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The Agilent Bio MAb NP10 column, sized at 2.1 x 50 mm and constructed with robust PEEK hardware, is engineered for the precise characterization and analysis of monoclonal antibodies and related biotherapeutics. This column features a specialized NP10 stationary phase designed for optimal high-resolution separation of immunoglobulin G and other protein variants, offering exceptional reproducibility and minimized non-specific binding. Its compact dimensions facilitate high-throughput workflows, making it ideal for both screening and detailed analysis in biopharmaceutical research and quality control environments.

This Bio MAb column demonstrates compatibility with a wide range of Agilent LC and UHPLC systems, including those commonly employed in biopharma laboratories. It supports native and denaturing modes, enabling versatile applications such as aggregate analysis, charge variant profiling, and glycosylation studies. The PEEK hardware ensures chemical resistance for extended column lifetime and reduced risk of sample interaction with metal surfaces, making it well-suited for sensitive biomolecule analysis.

Ideal for deployment in analytical laboratories focused on therapeutic antibody development, quality assurance, and regulatory compliance, this column integrates seamlessly with other Agilent bioseparation columns and solutions for comprehensive biotherapeutic characterization workflows.