Agilent, 635950-702, 1 AdvanceBio Oligonucleotide,10 x 100 mm, 2.7 µm

1 AdvanceBio Oligonucleotide,10 x 100 mm, 2.7 µm. Reversed-phase HPLC column designed for high-resolution IP-RP separation of oligos. Scalable chemistry platform supports analytical through prep purification for optimal resolution, yield, and purity. The 2.7µm, 10 mm semi-prep column dimensions enable fit-for-purpose benchtop purification on analytical instruments to maximize resources.

Specifications:
Brand: AdvanceBio Oligonucleotide
Guard Column: No
Hardware: SS
Inner Diameter (ID): 10 mm
LC Platform: Stainless Steel
Length: 100 mm
Maximum Temperature: 65 °C
Particle Size: 2.7 µm
Particle Type: Superficially Porous
Phase: HPH-C18
Pore Size: 120 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LC & LC/MS
pH Range: 3-11

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The AdvanceBio Oligonucleotide 10 x 100 mm, 2.7 µm column provides high-resolution, reliable separation of synthetic oligonucleotides and nucleic acid-based molecules for research and quality control environments. Engineered with advanced 2.7 µm superficially porous particles, this column delivers exceptional peak shape and sensitivity, allowing for precise analysis and quantification of oligonucleotides, including modified and therapeutic sequences. The unique design ensures robust performance across a range of mobile phases and gradient conditions, making it ideal for analyzing antisense oligonucleotides, siRNAs, aptamers, and other biopharmaceuticals. Frequently used in pharmaceutical development, genomics research, and bioprocess monitoring, this column supports methods development and routine QC workflows. It is fully compatible with Agilent 1290 Infinity II and 1260 Infinity II LC systems, as well as other HPLC and UHPLC platforms configured for bioseparations. For enhanced workflows, it pairs seamlessly with Agilent AdvanceBio Oligonucleotide standards and reagents, facilitating reproducible and consistent results. Rigorously tested to meet Agilent specifications, this column provides dependable reproducibility, longevity, and performance for laboratories seeking robust oligonucleotide analysis solutions.