Agilent, 699971-702, AdvanceBio Oligonucleotide, 4.6 x 50 mm, 4 µm

AdvanceBio Oligonucleotide, 4.6 x 50 mm, 4 µm. HPLC columns offer a high-quality, high-resolution IP-RP column chemistry platform that support analytical characterization through purification with method scale-up. The 4µm, 4.6 mm analytical scale column dimensions simplify method development calculations and optimization when translating your analytical method to larger inner diameter preparative dimensions for purification.

Specifications:
Brand: AdvanceBio Oligonucleotide
Guard Column: Yes
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: HPLC
Length: 50 mm
Maximum Temperature: 65 °C
Particle Size: 4 µm
Particle Type: Superficially Porous
Phase: HPH-C18
Pore Size: 120 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LC & LC/MS
pH Range: 3-11

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Designed to meet the demanding needs of oligonucleotide analysis, this high-performance column features a 4.6 x 50 mm geometry with 4 micron particle size for exceptional resolution and sensitivity. Engineered for the separation and characterization of synthetic oligonucleotides, it delivers reliable and reproducible results for researchers working in nucleic acid therapeutics, genetic research, and quality control environments. Its optimized packing material provides superior peak shape and minimizes carryover, enabling efficient analysis of diverse oligonucleotide lengths and modifications.

Ideally suited for reversed-phase liquid chromatography methods, this column is compatible with Agilent 1260 Infinity II, 1290 Infinity II, and other major HPLC and UHPLC systems, ensuring seamless integration into existing laboratory workflows. Typical applications include impurity profiling, purity assessment, and quantitation of oligonucleotide samples.

For streamlined performance, it can be paired with Agilent AdvanceBio buffers and sample preparation products. This robust solution supports analytical method development and routine QC testing, providing accurate and reproducible results across a range of oligonucleotide types. With its advanced design and versatility, it is an essential tool for pharmaceutical, biotechnology, and academic laboratories engaged in nucleic acid research and development.