Agilent, 770995-902, ZORBAX Extend 300 C18, 4.6 x 250 mm, 5 µm

ZORBAX Extend 300 C18, 4.6 x 250 mm, 5 µm. A reversed-phase C18 HPLC column with fully porous ZORBAX particles. The 300-Extend C18 chemistry incorporates a unique bidentate silane which allows the column to withstand pH up to 11.5.

Specifications:
Brand: ZORBAX
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 250 mm
Maximum Temperature: 40 °C at pH 8-11.560 °C at pH 6-8
Part Number Application Domain: Biopharma
Part Number Application: Monoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 5 µm
Particle Type: Fully Porous
Phase: Extend-C18
Pore Size: 300 Å
Pressure Rating: 400 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115709
pH Range: 2-11

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The ZORBAX Extend 300 C18 column with dimensions of 4.6 x 250 mm and a 5 micron particle size is engineered for high-performance liquid chromatography. Designed specifically to deliver robust separation of peptides, proteins, and other large biomolecules, this column features an extended pH stability from 2 to 11, making it suitable for a wide array of analytical and preparative applications in proteomics, pharmaceutical development, and biotherapeutic characterization. Its 300 Angstrom pore size allows for efficient analysis of high molecular weight compounds, maintaining peak shape and resolution even for challenging analytes.

This reverse-phase column is compatible with major HPLC and UHPLC systems, ensuring seamless integration into existing workflows across research and quality control laboratories. It is often employed in method development for peptide mapping, protein purity assessment, and glycoprotein profiling. The column is recommended for use with Agilent LC systems and is fully compatible with other Agilent ZORBAX columns for flexible method scalability. Additionally, it pairs well with a range of mobile phases across varying pH conditions, providing versatility for both routine and specialized separations. Its durable design ensures prolonged column life and consistent performance, even under demanding operating conditions.