Agilent, 793775-904, AdvanceBio RP-mAb C4, 2.1 x 150 mm, 3.5 µm

AdvanceBio RP-mAb C4, 2.1 x 150 mm, 3.5 µm. A reversed-phase C4 HPLC column with superficially porous particles and a wide (450 Å) pore size designed for mAbs and other larger proteins for intact or subunit analysis.

Specifications:
Brand: AdvanceBio RP mAb C4
Hardware: SS
Inner Diameter (ID): 2.1 mm
LC Platform: Stainless Steel
Length: 150 mm
Maximum Temperature: 90 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 3.5 µm
Particle Type: Superficially Porous
Phase: C4
Pore Size: 450 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-8

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The AdvanceBio RP-mAb C4 column, sized 2.1 x 150 mm and packed with 3.5 micron particles, is designed for high-resolution reversed-phase chromatographic separation of monoclonal antibodies and related biotherapeutics. Tailored for both intact and subunit mAb analysis, this column delivers outstanding performance in assessing product purity, stability, and heterogeneity, making it ideal for pharmaceutical research, development, and quality control workflows. The C4 bonded phase ensures optimal hydrophobic interaction with large biomolecules, facilitating reproducible peptide mapping and characterization.

This product is compatible with a wide range of UHPLC and HPLC systems, including Agilent 1200 Infinity and 1290 Infinity II LC platforms, while also integrating seamlessly with mass spectrometry for advanced characterization needs. The 2.1 mm internal diameter enables efficient handling of limited sample volumes, while the 150 mm length provides substantial resolving power for complex sample matrices. Related offerings in the AdvanceBio column family enable complementary analyses across different protein classes and molecular weights, supporting comprehensive biologics workflows. This solution is a trusted choice for analytical scientists focused on the fast and reliable separation of mAbs, biosimilars, or other large proteins in both research and regulated laboratory settings.