BRAND / VENDOR: Agilent

Agilent, GX96-201PC, AdvanceBio Gly-X deglycosylation and InstantPC labeling module set, 96-ct

CATALOG NUMBER: GX96-201PC

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Product Description
AdvanceBio Gly-X deglycosylation and InstantPC labeling module set, 96-ct. Utilizes a novel in-solution enzymatic protein deglycosylation followed by rapid labeling of released N-glycans with InstantPC dye. With deglycosylation and labeling carried out in solution, the method is simple, rapid, and suitable for automation. The InstantPC dye delivers unmatched fluorescent brightness and MS signal, which enables a single labeling method to be deployed across different glycan analysis workflows. Includes GX96-100 Gly-X deglycosylation module,
GX96-101 Gly-X InstantPC labeling module. For cleanup use GX96-102 Gly-X InstantPC cleanup module. Specifications: Application: Flexible, high-throughput format:process 1 to 96 samples Count: 96 Equipment & Reagents Provided by User: Thermocycler (Corning THERM-1001, 110V. THERM-1000, 230V). Note:Two GlykoPrep heaters, WS0271, can be fitted with VWR 13259-260 modular heating blocks Kit Configuration: Sample Prep Module Set Label: InstantPC Precision (well-to-well, day-to-day): <5% CV Prep time (approx): 42 min (16 samples), 99 min (96 samples) Preservation of Sialylated Species: > 95 % Protein Load Range: 1-40 µg Recovery: > 95 % Stability: Samples may be stored at -20°C for up to 6 months in Gly-X InstantPC eluent, or 4°C for up to 5 days in either Gly-X InstantPC eluent or after dilution with ACN/DMF Technique: LC & LC/MS **********The following product description is generated by AI and is for reference only. If you have any questions, please contact customer service.********** This module set provides an integrated solution for rapid N-glycan sample preparation and labeling workflows in biopharmaceutical research. Designed for high throughput, the kit includes pre-filled reagents and consumables for enzymatic deglycosylation and advanced InstantPC fluorescent labeling, enabling streamlined processing of up to 96 samples in a single run. The workflow significantly reduces preparation time compared to traditional methods, offering consistent and efficient glycan release and derivatization. Ideal for researchers analyzing monoclonal antibodies, fusion proteins, and other glycoproteins, the set delivers reproducible results and high sensitivity for glycan profiling by liquid chromatography and mass spectrometry. Applications include lot-to-lot characterization, comparability studies, biosimilar development, and quality control in bioprocessing. The reagents are optimized for compatibility with Agilent UHPLC, LC-MS, and CE systems, such as the AdvanceBio LC columns and 6545XT AdvanceBio LC/Q-TOF. This ensures seamless integration into existing analytical workflows and reliable performance. Extensive documentation and protocol support further enhance usability in regulated laboratory environments. For best results, pairing with Agilent AdvanceBio sample preparation kits and analytical columns is recommended to ensure uniformity and traceability across glycan analysis workflows.
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