Agilent, PL1212-4100, PLRP-S 100Å, 25 x 25 mm, 10 µm, guard

PLRP-S 100Å, 25 x 25 mm, 10 µm, guard. Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Guard Column: Yes
Hardware: SS
Inner Diameter (ID): 25 mm
LC Platform: Stainless Steel
Length: 25 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: PeptidesPreparative HPLC Columns & Bulk MediaProteins
Particle Size: 10 µm
Particle Type: Fully Porous
Phase: DVB
Pore Size: 100 Å
Pressure Rating: 207 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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Designed for high-performance liquid chromatography (HPLC) applications, this guard column cartridge features a 100 Angstrom pore size, a 25 x 25 mm dimension, and a 10 micron particle size. Utilizing styrene-divinylbenzene chemistry, it provides excellent mechanical and chemical stability, making it suitable for demanding reversed-phase separations, particularly of biomolecules and synthetic polymers. The guard format ensures effective protection of the main analytical column by trapping particulates and strongly adsorbed contaminants, extending column lifespan and preserving performance. This component is ideal for laboratories conducting protein, peptide, oligonucleotide, or hydrophobic analyte analysis under a range of mobile phase conditions, including high temperatures and organic solvents. It is especially well-suited for applications requiring rigorous sample cleanliness and consistent chromatographic results. Compatible with a range of Agilent and third-party HPLC systems, it seamlessly integrates into existing setups using appropriate hardware. It is often paired with Agilent’s main PLRP-S analytical columns, enabling researchers to achieve reproducible results with minimized downtime due to column fouling. This guard column is a reliable accessory for both routine and advanced research in pharmaceutical, biotechnology, environmental, and polymer analysis workflows.