BD, 334098, BD™ Anti-Human CD86 PE/CD209 PerCP-Cy™5.5/CD83 APC

Reactivity: Human
Application: Flow cytometry
Regulatory Status: RUO (GMP)
RRID: AB_2074438
Storage Buffer: Phosphate buffered saline with BSA, beta-lactoglobulin, and 0.1% sodium azide.
Description: Description CD86, clone FUN-1, is derived from hybridization of Sp-2 x HBL-1. CD209, clone DCN46, is cloned from a placental library. CD83, clone HB15e, is derived from Balb/c x NS-1. The CD86 antibody recognizes a 75-kilodalton (kDa) cell-surface protein, a second ligand for CD28 and CTLA-4 expressed on T cells. The CD209 antibody recognizes a dendritic cell–specific ICAM-3–grabbing nonintegrin (DC-SIGN). The CD209 antigen is a type II membrane protein of approximately 44 kDa, with a mannose-binding, C-type lectin domain exclusively expressed by dendritic cells, both in vitro–generated MDDCs and dendritic cells in several tissues, including mucosa and lymph nodes. The CD83 antibody reacts with a 45-kDa transmembrane protein member of the Ig superfamily and is composed of a single V-type Ig extracellular domain with a Cterminal cytoplasmic tail.
Preparation And Storage: Preparation And Storage Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.
Description : Clone : Isotype : EntrezGene ID
N/A : N/A : | IgG1, κ,IgG1, κ,IgG2b, κ : N/A