Cytiva, NOS0011, NanoAssemblr™ Spark™ nanoparticle formulation system

Instrument training for NanoAssemblr™ Spark™ The NanoAssemblr™ Spark™ nanoparticle formulation system enables the production of nanoparticle formulation in volumes ranging from 25 – 250 μL, ideal for discovery and screening that involves scarce or expensive nucleic acids and nanoparticle excipients. • Robust process and feedback - Electronic control minimizes batch-to-batch and user variability while providing real-time feedback to help optimize your formulation • Rapid production - Simply pipette starting materials into wells, and with the press of a button, the formulation is ready in seconds, allowing hundreds of formulations to be made in just a few hours • Workflow integration - Designed for operation in a sterile biosafety hood, the formulations can be made on-demand and applied to cells in culture • Scalable – Leveraging NxGen™ mixing technology, the formulations can be seamlessly scaled across the NanoAssemblr™ platform, accelerating future development • Exceptional sample recovery - Advanced NxGen™ mixing technology allows the formulation of microliter volumes with near complete sample recovery The Nanoassemblr™ Spark™ system enables robust low-volume RNA-lipid nanoparticle (LNP) formulations ideal for drug discovery and early preclinical development. Simple, easy workflow Formulations on the Nanoassemblr™ Spark™ system are ready in seconds. Plus, they can be made on-demand in a sterile hood for immediate cell culture applications. Applications Nucleic acid delivery and screening Nanoparticle design and screening Drug discovery and target validation Related products NanoAssemblr™ Spark™ cartridges NanoAssemblr™ Spark™ cartridges are equipped with NxGen™ mixing technology. No cleaning or validation is required: cartridges are single-use and gamma-irradiated. Pressure test cartridges Pressure test cartridges can be used to ensure optimal functioning of your system. Read the user guide below to learn more. Reagents Expand formulation capabilities and advance genomic medicines with specialized accessories and optimized LNP delivery reagents . GenVoy-ILM™ T Cell Kit for mRNA The GenVoy-ILM™ T Cell Kit for mRNA is a lipid nanoparticle reagent mix optimized for the delivery of mRNA into activated primary human T cells using mRNA-LNP. Cytiva CD34+ HSC LNP kit, 100 μL The Cytiva CD34+ HSC LNP kit, 100 μL enables the delivery of RNA into hematopoietic stem cells for ex vivo gene delivery and knockout.