Cytiva, XT40MSTGQP05, Mustang™ Q XT chromatography membrane capsules

Mustang™ Q XT40 (40 mL) capsule Mustang™ membrane chromatography capsules, a Pall Life Sciences product, are robust, easy to use and enable users to significantly optimize their process by minimizing buffer consumption, increasing throughput and reducing capital expenditure. • Binding efficiency: Mustang™ Q XT capsules exhibit high capacities and high flow at low pressure drops, allowing binding of large charged biomolecules such as plasmids and lentiviruses in a single pass. • Speed: Membrane binding capacity is not significantly affected by flow rate. Mustang™ Q capsules typically operate at 10 MV/min flow rates (up to 50 L/min for XT5000), enabling membrane chromatography to process much faster than conventional chromatography sorbents. High flow rates enable the processing of large volumes in less than a single working shift • Reproducible: Capsules are manufactured using the Statistical Process Control (SPC) system to enable the process to be reproduced in a consistent manner. • Scalable and Flexible: A full range of capsule sizes accommodates various volumes and capacities required in biopharmaceutical processing, from process development to full-scale manufacturing. • Convenient: Ready-to-use and disposable to eliminate potential packing, cleaning, validation, and cross-contamination issues. • Cost: Membrane capsules offer lower operating and capital investment costs than conventional columns that require validated packing and cleaning protocols. • Reduced buffer Consumption: The small device footprint requires significantly less buffer yet maintains efficient contaminant removal performance. Screening and optimization studies can be performed with full confidence as Mustang™ Q capsules, XT5 to XT5000, are made with the same construction materials and consistent void volume-to-membrane ratio, for scalable chromatographic performance. The XT5 device, is ideal for scale-down optimization studies. Combining high capacity, ion-exchange Mustang™ membranes with a unique 16-layer open-pleat design results in a high-flow rate, high capacity, single-use, versatile range of pleated products that can be used for a wide range of applications. Mustang™ Q XT capsules with the same membrane technology and smaller membrane volumes are proven in a wide range of approved processes and clinical trials for applications such as: Capture of lentiviruses Plasmid purification
Adeno-associated virus (AAV) and adenoviruses purification Purification of large protein Monoclonal antibody polishing