Waters, 186008948, BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 3 mm X 50 mm, 1/pk

The first choice for reverse phase protein separation and analysis, BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 3 mm X 50 mm Columns contain 2.7 µm superficially-porous-silica particles having an average pore diameter of 450Å. The particles are functionalized with a proprietary polyphenyl bonding process that was specifically designed for LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments. Each batch is qualified using a gradient separation of the Waters mAb Subunit Standard (p/n: 186008927). Note: p/n: 176004162 contains this same column with Intact mAb Mass Check Standard (p/n: 186006552) and mAb Subunit Standard (p/n: 186008927). Suggested Use: Intact protein and mAb subunit analysis, Protein Analysis, ADC characterization, AAV, Antibody Conjugates

Specifications
Separation Mode: Reversed Phase
Temperature Limits: 90 C
Maximum Pressure: 10000 psi (689 Bar)
Particle Size: 2.7 µm
Pore Size: 450 Å
QC Tested: Protein
System: HPLC, UHPLC, UPLC
USP Classification: L11
UNSPSC: 41115709
Brand: BioResolve
Product Type: Columns
Units per Package: 1 pk

Additional Information
BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 3 mm X 50 mm, 1/pk Solving analytical challenges inherent in biotherapeutic drug analysis can sometimes be difficult, which is why you should only use a chromatography column that’s capable of handling those challenges with ease. And with the BioResolve RP mAb Polyphenyl Column, you get exactly that. This breakthrough monoclonal antibody analysis tool offers a group of superficially-porous silica particles that are then functionalized with a polyphenyl bonding process to provide incredible throughput and sensitivity despite overwhelming chromatographic conditions. What’s more, you can even equip the BioResolve RP mAb Polyphenyl Column with VanGuard column protection to increase its overall lifetime and performance. Add the BioResolve RP mAb Polyphenyl Column to your lab’s procurement list or order one directly from us today. There are so many challenges that you come across in the intact protein analysis of monoclonal antibodies and antibody drug conjugates, but the BioResolve RP mAb Polyphenyl Column makes easy work of overcoming them all. Part of that is because of the novel polyphenyl bonding process that’s used to functionalize the porous silica particles within the column. Another reason is because this mAb separation tool can be used on all UHPLC, UPLC and HPLC systems. That means increased flow rates and back pressures are of no great concern to this column, which is perfect for scientists working exclusively in method development. In addition to a wide and usable pH range that can accommodate varying analytes, the BioResolve RP mAb Polyphenyl Column also exhibits minimal injection-to-injection carryover for increased confidence in analyses. But to greatly increase confidence assay after assay, we recommend equipping your BioResolve RP mAb Polyphenyl Column with the BioResolve RP mAb Polyphenyl VanGuard Cartridge . This guard cartridge seamlessly incorporates into your existing workflow to protect your analytical column from fouling caused by particulate contaminants. Plus, this cartridge can increase your column’s overall lifetime, so you can get back to the experiments that truly matter time and again. At Waters, we offer much more than just BioResolve RP mAb Polyphenyl Columns that can help you overcome analytical challenges. We also offer a truly massive selection of products and resources to help improve your lab’s overall efficiency and profitability. Shop lab equipment to discover everything we have to offer.

FAQ
What’s the Pore Size of the BioResolve RP mAb Polyphenyl Column? The BioResolve RP mAb Polyphenyl Column offers a pore size of 450 Å.