Agilent, 5190-2518, Agilent Bio SEC-5, 100Å, 4.6 x 300 mm, 5 µm

Agilent Bio SEC-5, 100Å, 4.6 x 300 mm, 5 µm. A size exclusion column for aggregate analysis of peptides and small proteins. Resolving range 0.1-100 kDa.

Specifications:
Brand: Agilent Bio SEC-5
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 300 mm
Maximum Temperature: 80 °C
Molecular Weight Lower Limit: 100 Da
Molecular Weight Upper Limit: 100000 Da
Part Number Application Domain: Biopharma
Part Number Application: Aggregate & Fragment AnalysisPeptidesProteins
Particle Size: 5 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 100 Å
Pressure Rating: 240 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-8.5

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The Agilent Bio SEC-5, 100 Å, 4.6 x 300 mm, 5 µm column is engineered for high-resolution size exclusion chromatography of proteins, peptides, and biopolymers. Featuring a 100 Å pore size and a 5 µm particle size, this column delivers precise separation of biomolecules in the molecular weight range typical for peptides and small proteins. Its high-purity, hydrophilic silica support minimizes non-specific interactions, ensuring reproducible and accurate molecular size determinations with low sample adsorption.

This column is ideal for analytical labs conducting quality control, characterization, and quantitation of therapeutic proteins, protein aggregates, and biosimilars. It is commonly used in pharmaceutical development, bioprocess monitoring, and academic research demanding robustness and reproducibility.

Designed for compatibility with Agilent HPLC and UHPLC systems, such as the 1260 Infinity II and 1290 Infinity LC series, it integrates seamlessly with a wide range of detectors including UV, fluorescence, and light scattering. The column also pairs effectively with Agilent’s SEC calibration standards and mobile phase solutions, providing a comprehensive workflow solution for size-based biomolecular analysis. Each column is tested for efficiency and durability, supporting reliable, high-throughput laboratory performance.