Agilent, 5190-2531, Agilent Bio SEC-5, 500Å, 7.8 x 300 mm, 5 µm

Agilent Bio SEC-5, 500Å, 7.8 x 300 mm, 5 µm. A size exclusion column for aggregate analysis of large biological samples such as adeno associated virus. Resolving range 15 kDa - 5 MDa.

Specifications:
Brand: Agilent Bio SEC-5
Hardware: SS
Inner Diameter (ID): 7.8 mm
LC Platform: Stainless Steel
Length: 300 mm
Maximum Temperature: 80 °C
Molecular Weight Lower Limit: 15000 Da
Molecular Weight Upper Limit: 5000000 Da
Part Number Application Domain: Biopharma
Part Number Application: Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 5 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 500 Å
Pressure Rating: 240 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-8.5

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The Agilent Bio SEC-5, 500Å, 7.8 x 300 mm, 5 µm column is engineered for high-resolution size exclusion chromatography (SEC) of proteins, peptides, and biomolecules. Designed with a pore size of 500 angstroms and uniform 5 micron particles, this column delivers precise molecular weight separation for a broad range of analytical and preparative applications. Its robust silica-based construction ensures excellent reproducibility and mechanical stability, making it an optimal choice for both routine quality control and advanced biomolecular research.

Commonly used in the analysis of monoclonal antibodies, protein aggregates, and other large biomolecules, this column is suitable for applications such as aggregate analysis, purity assessment, and characterization studies. It supports aqueous and organic SEC methods, providing flexibility for diverse sample types. The column is compatible with Agilent InfinityLab LC systems, as well as other standard HPLC instrumentation, facilitating seamless integration into existing laboratory workflows. For extended workflow capabilities, it can be paired with complementary columns in the Agilent Bio SEC portfolio. Rigorous manufacturing standards and strict quality control ensure reliable, reproducible performance, making this column a trusted solution for sensitive biopharmaceutical and protein research.