Agilent, 5190-6848, Agilent Bio SEC-3, 300Å, 4.6 x 50 mm, 3 µm, guard

Agilent Bio SEC-3, 300Å, 4.6 x 50 mm, 3 µm, guard. A size exclusion guard column to protect and extend the lifetime of a longer analytical SEC column.

Specifications:
Brand: Agilent Bio SEC-3
Guard Column: Yes
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 80 °C
Molecular Weight Lower Limit: 5000 Da
Molecular Weight Upper Limit: 1250000 Da
Part Number Application Domain: Biopharma
Part Number Application: Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 3 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 300 Å
Pressure Rating: 240 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-8.5

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Designed for high-resolution size exclusion chromatography, this advanced guard column protects and extends the lifespan of analytical columns by efficiently removing particulates and contaminants from biological samples. Featuring a 300 angstrom pore size and 3 micron particle size, it delivers precise separation of proteins, peptides, and other biomolecules based on molecular size. The compact 4.6 x 50 millimeter dimension ensures minimal sample loss and rapid analysis, making it ideal for fast quality control and research workflows.

This guard is especially suitable for applications in biopharmaceutical characterization, aggregate analysis, and protein purity assessment. It integrates seamlessly with Agilent’s Bio SEC-3 analytical columns and fits most standard HPLC and UHPLC systems, including those from Agilent’s InfinityLab and 1260/1290 series. Researchers and analytical scientists benefit from improved column protection, consistent separation performance, and easy installation.

Compatible with a variety of aqueous mobile phases, this guard is well-suited for routine SEC analyses in protein laboratories and bioprocessing environments. Pairing it with other Agilent Bio SEC-3 main columns allows for robust, reproducible, and reliable results when screening monoclonal antibodies, vaccines, enzymes, or complex protein formulations.