Agilent, 635750-702, 1 AdvanceBio Oligonucleotide,10 x 100, 4 µm

1 AdvanceBio Oligonucleotide,10 x 100, 4 µm. Reversed-phase HPLC column designed for high-resolution IP-RP separation of oligos. Scalable chemistry platform supports analytical through prep purification for optimal resolution, yield, and purity. The 4µm, 10 mm semi-prep column dimensions enable fit-for-purpose benchtop purification on analytical instruments to maximize resources.

Specifications:
Brand: AdvanceBio Oligonucleotide
Guard Column: No
Hardware: SS
Inner Diameter (ID): 10 mm
LC Platform: Stainless Steel
Length: 100 mm
Maximum Temperature: 65 °C
Particle Size: 4 µm
Particle Type: Superficially Porous
Phase: HPH-C18
Pore Size: 120 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LC & LC/MS
pH Range: 3-11

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This column is specifically engineered for high-resolution analysis of oligonucleotides in a range of genomics and biopharmaceutical research applications. Featuring a particle size of 4 microns and dimensions of 10 x 100 millimeters, it delivers excellent separation efficiency, allowing for precise characterization of synthetic and naturally occurring oligos, including siRNA, antisense oligonucleotides, and aptamers. Its robust packing technology ensures consistent performance and reproducible results, making it an optimal choice for laboratories conducting quality control, method development, and comprehensive profiling of nucleic acid therapeutics.

The column is compatible with a range of high-performance liquid chromatography HPLC and ultra-high-performance liquid chromatography UHPLC systems, making it a versatile addition to Agilent and other major instrument platforms. It pairs seamlessly with Agilent LC systems such as the 1290 Infinity II for enhanced sensitivity and throughput. Additionally, the column supports both ion-pair reversed-phase and ion-exchange separation modes, expanding its utility across different analytical workflows. Researchers benefit from its reliable performance across a spectrum of buffer conditions, facilitating a wide variety of sequence and modification analyses. This product is part of Agilents comprehensive suite of oligonucleotide analysis solutions, providing synergy when combined with related sample preparation and detection technologies.