Agilent, 639750-702, 1 AdvanceBio Oligonucleotide,10 x 50, 4 µm

1 AdvanceBio Oligonucleotide,10 x 50, 4 µm. Reversed-phase HPLC column designed for high-resolution IP-RP separation of oligos. Scalable chemistry platform supports analytical through prep purification for optimal resolution, yield, and purity. The 4µm, 10 mm semi-prep column dimensions enable fit-for-purpose benchtop purification on analytical instruments to maximize resources.

Specifications:
Brand: AdvanceBio Oligonucleotide
Guard Column: No
Hardware: SS
Inner Diameter (ID): 10 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 65 °C
Particle Size: 4 µm
Particle Type: Superficially Porous
Phase: HPH-C18
Pore Size: 120 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LC & LC/MS
pH Range: 3-11

**********The following product description is generated by AI and is for reference only. If you have any questions, please contact customer service.**********
Designed for high-resolution analysis and purification of synthetic oligonucleotides, this column offers optimal performance in research and quality control laboratories. Featuring a 10 x 50 mm dimension and 4-micron particle size, it enables efficient separation with high sensitivity, making it ideal for applications such as antisense oligonucleotide characterization, siRNA profiling, and quality assessment of modified nucleic acids. Its robust silica-based chemistry delivers consistent peak shapes and reproducibility across a wide range of oligonucleotide lengths and modifications.

This column is fully compatible with Agilent HPLC and UHPLC systems, as well as other standard liquid chromatography instruments, providing flexibility for various laboratory workflows. Researchers benefit from increased throughput and reliable data, particularly in environments requiring stringent purity validation for therapeutic oligonucleotides or advanced nucleic acid therapeutics. Its design supports both analytical and preparative workflows, accommodating a variety of sample types and buffer systems.

Integrating seamlessly with other Agilent AdvanceBio columns and consumables, this component supports comprehensive biomolecule analysis within genomics, biotechnology, and pharmaceutical research. Its durability under demanding gradient and temperature conditions ensures low maintenance and consistent performance, facilitating routine and advanced oligonucleotide analysis.