Agilent, 659950-702, AdvanceBio Oligonucleotide, 4.6 x 50 mm, 2.7 µm

AdvanceBio Oligonucleotide, 4.6 x 50 mm, 2.7 µm. Reversed-phase HPLC column designed for high-resolution IP-RP separation of oligos. Scalable chemistry platform supports analytical through prep purification for optimal resolution, yield, and purity.

Specifications:
Brand: AdvanceBio Oligonucleotide
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 65 °C
Part Number Application: Oligos
Part Number Application Domain: BiopharmaPharmaceutical
Particle Size: 2.7 µm
Particle Type: Superficially Porous
Phase: HPH-C18
Pore Size: 120 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LC & LC/MS
UNSPSC Code: 41115711
pH Range: 3-11

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Designed for high-resolution and high-throughput analysis, this 4.6 x 50 mm, 2.7 µm chromatographic column offers reliable performance in oligonucleotide separations. Utilizing advanced superficially porous particle technology, the column delivers superior efficiency and sharp peak shapes, making it an excellent choice for both qualitative and quantitative analyses of synthetic oligonucleotides, antisense therapeutics, siRNA, and other modified nucleic acids. Its robust design ensures consistent reproducibility across multiple runs, supporting demanding applications such as impurity profiling, method development, and purity assessment in pharmaceutical and biotechnology research environments.

Ideal for reverse-phase liquid chromatography, this column is fully compatible with Agilent’s range of UHPLC and HPLC systems, including the Agilent InfinityLab and 1200 Series platforms. It integrates seamlessly with Agilent’s AdvanceBio family of biopharmaceutical analysis products, facilitating streamlined workflows for nucleic acid characterization. Suitable for researchers working in oligonucleotide synthesis, therapeutic development, and quality control labs, this column is optimized for use with common mobile phases and analytes, providing reliable data for regulatory compliance and discovery projects. Its durability and versatility support a wide array of analytical protocols, ensuring consistent performance in both routine and advanced research applications.