Agilent, 671050-702, AdvanceBio Oligonucleotide, 21.2 x 50 mm, 4 µm

AdvanceBio Oligonucleotide, 21.2 x 50 mm, 4 µm. HPLC columns offer a high-quality, high-resolution IP-RP column chemistry platform that support analytical characterization through purification with method scale-up. The 4µm, 21.2 mm preparative column dimensions offer high resolution for optimal yield and purity of your target product.

Specifications:
Brand: AdvanceBio Oligonucleotide
Guard Column: No
Hardware: SS
Inner Diameter (ID): 21.2 mm
LC Platform: Preparative HPLC
Length: 50 mm
Maximum Temperature: 65 °C
Particle Size: 4 µm
Particle Type: Superficially Porous
Phase: HPH-C18
Pore Size: 120 Å
Pressure Rating: 400 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LC & LC/MS
pH Range: 3-11

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Designed for high-performance analysis of oligonucleotides, this 21.2 x 50 mm column utilizes advanced 4 micron particle technology to deliver superior separation, sensitivity, and reproducibility. Ideal for researchers working in nucleic acid therapeutics, academic research, and quality control environments, the column is optimized for reversed-phase liquid chromatography methods, enabling precise characterization and quantification of synthetic or modified oligonucleotides including siRNA, aptamers, and antisense oligos. It achieves excellent resolution of closely related oligonucleotide sequences, supporting method development and impurity profiling. Compatible with Agilent 1260 Infinity II and 1290 Infinity II LC systems as well as other UHPLC and HPLC platforms, the column seamlessly integrates into existing analytical workflows. It is designed for robust performance under a variety of mobile phase conditions, enhancing analytical flexibility. Use this product as part of the Agilent AdvanceBio family for streamlined oligonucleotide analysis, and combine with Agilent sample preparation kits and LC-MS solutions for comprehensive nucleotide studies. This column is an excellent choice for consistent data quality in demanding biopharmaceutical and genomic applications, supporting regulatory compliance and advanced research needs.