Agilent, 673775-901, AdvanceBio MS Spent Media, 100 Å, 2.1 x 150 mm, 2.7 µm

AdvanceBio MS Spent Media, 100 Å, 2.1 x 150 mm, 2.7 µm. Zwitterionic HILIC column that delivers fast, sensitive, and reproducible separations of underivatized amino acids and polar metabolites found in bioprocessor cell culture media for LC-MS detection.

Specifications:
Brand: AdvanceBio MS Spent Media
Hardware: PEEK Lined SS
Inner Diameter (ID): 2.1 mm
LC Platform: BioInert
Length: 150 mm
Maximum Temperature: 80 °C
Part Number Application: Spent Media Analysis
Part Number Application Domain: Biopharma
Particle Size: 2.7 µm
Particle Type: Superficially Porous
Phase: HILIC-Z
Pore Size: 120 Å
Pressure Rating: 600 bar
Separation Mode: HILIC
Shipping Solvent: Acetonitrile/Water
Technique: LC & LC/MS
UNSPSC Code: 41115709
pH Range: 3-11

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Designed for high-resolution analysis of complex biotechnology samples, this column is optimized for the robust and reproducible characterization of spent cell culture media. Featuring a 100 Å pore size and 2.7 µm particle technology within a 2.1 x 150 mm format, it offers excellent efficiency and peak capacity, enabling detailed profiling of proteins, peptides, and metabolites present in bioprocess monitoring or quality control workflows. The column is intended for use with UHPLC and LC-MS systems, making it well-suited for laboratories engaged in therapeutic protein production, process development, and cell culture optimization. It is compatible with Agilent AdvanceBio LC systems, as well as other major UHPLC platforms. Reliable and consistent performance supports high-throughput screening and in-depth analysis, facilitating rapid method development and routine QC applications. The stationary phase ensures low carryover and optimal sensitivity, addressing the challenges of sample complexity in spent media analysis. For comprehensive workflow solutions, this column integrates seamlessly with related Agilent AdvanceBio MS columns and sample preparation kits. Its durable construction ensures long-lasting use while maintaining exceptional separation quality, making it an ideal choice for biopharmaceutical research, process analytical technology, and proteomics studies.