Agilent, 681975-908K, AdvanceBio HIC, 4.6 × 30 mm, 3.5 µm, method validation kit

AdvanceBio HIC, 4.6 × 30 mm, 3.5 µm, method validation kit. Includes three columns from different batches

Specifications:
Brand: AdvanceBio HIC
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 100 mm
Maximum Temperature: 60 °C
Part Number Application Domain: Biopharma
Particle Size: 3.5 µm
Particle Type: Fully Porous
Pore Size: 450 Å
Pressure Rating: 400 bar
Separation Mode: Hydrophobic Interaction (HIC)
Shipping Solvent: Acetonitrile
UNSPSC Code: 41115709
pH Range: 2-8

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Designed for robust hydrophobic interaction chromatography, this method validation kit offers a 4.6 × 30 mm column format with 3.5 µm particle size, providing reliable separation and quantitation of proteins, antibodies, and other biomolecules. Optimized for high-throughput analysis, the kit supports efficient method validation, including reproducibility, specificity, and linearity assessments in pharmaceutical and biotherapeutic research workflows.

Engineered with tightly controlled particle and pore characteristics, the column ensures high resolution and consistent retention, facilitating detection of subtle differences in protein or antibody variants, aggregates, and impurities. Its short column dimensions are ideal for fast method development and validation, reducing solvent consumption and analysis time without sacrificing analytical performance.

The kit is fully compatible with a range of Agilent liquid chromatography systems, such as the 1290 Infinity II and 1260 Infinity II, as well as other major LC platforms equipped to handle hydrophobic interaction chromatography. It is suitable for integration into QC, process development, and research laboratories involved in biopharmaceutical characterization, stability studies, and lot-to-lot comparability.

For optimal performance, pairing with AdvanceBio buffers and associated application support is recommended, ensuring seamless implementation into existing protein analysis workflows. This kit is an essential solution for scientists requiring accurate, reproducible, and efficient hydrophobic interaction chromatography.