Agilent, 693971-702, 1 AdvanceBio Oligonucleotide, 4.6 x 150 mm, 4 µm

1 AdvanceBio Oligonucleotide, 4.6 x 150 mm, 4 µm. HPLC columns offer a high-quality, high-resolution IP-RP column chemistry platform that support analytical characterization through purification with method scale-up. The 4µm, 4.6 mm analytical scale column dimensions simplify method development calculations and optimization when translating your analytical method to larger inner diameter preparative dimensions for purification.

Specifications:
Brand: AdvanceBio Oligonucleotide
Guard Column: Yes
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: HPLC
Length: 150 mm
Maximum Temperature: 65 °C
Particle Size: 4 µm
Particle Type: Superficially Porous
Phase: HPH-C18
Pore Size: 120 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LC & LC/MS
pH Range: 3-11

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Engineered for high-resolution analysis of oligonucleotides, this 4.6 x 150 mm column with 4 micron particle size is an optimal solution for nucleic acid researchers seeking robust, reproducible results. Designed using proprietary bonded phase technology, it delivers precise separation of synthetic and modified oligonucleotides of varying lengths and complexities. This product is ideally utilized in pharmaceutical, biotechnology, and academic laboratories for quality control, purity assessment, and characterization of therapeutic oligonucleotides such as antisense RNAs, aptamers, and small interfering RNAs.

The column is compatible with a wide range of Agilent high-performance liquid chromatography platforms, including the 1100, 1200, and 1260 Infinity series systems. Its design supports both UV and mass spectrometry detection, enabling sensitive quantitative and qualitative analyses. The stationary phase ensures excellent peak shape and resolution, even for closely related oligos or challenging sequences.

Efficient, robust, and reproducible, this column provides seamless integration with Agilent AdvanceBio buffers and other nucleic acid workflow solutions. It is an ideal choice for scientists committed to advancing therapeutics development, ensuring regulatory compliance, or performing high-throughput screening of oligonucleotide libraries in drug discovery and genetic research environments.