Agilent, 793975-904, AdvanceBio RP-mAb C4, 4.6 x 150 mm, 3.5 µm

AdvanceBio RP-mAb C4, 4.6 x 150 mm, 3.5 µm. A reversed-phase C4 HPLC column with superficially porous particles and a wide (450 Å) pore size designed for mAbs and other larger proteins for intact or subunit analysis.

Specifications:
Brand: AdvanceBio RP mAb C4
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 150 mm
Maximum Temperature: 90 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 3.5 µm
Particle Type: Superficially Porous
Phase: C4
Pore Size: 450 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-8

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The AdvanceBio RP-mAb C4, 4.6 x 150 mm, 3.5 µm column is engineered for optimized reversed-phase separation of monoclonal antibodies, antibody fragments, and related biotherapeutics. Utilizing a robust 3.5 µm C4 bonded silica particle design, this column delivers high-efficiency resolution and reliable peak performance for both analytical and characterization workflows. It is ideal for applications including intact and subunit mAb purity assessment, charge variant separation, and high-throughput screening in biopharmaceutical research and development environments.

This column supports high sensitivity detection with exceptional reproducibility, making it suitable for quality control, process monitoring, and stability studies. Its 4.6 mm internal diameter accommodates increased sample loads and ensures compatibility with both conventional and UHPLC systems. The column integrates seamlessly with Agilent InfinityLab LC Series and 1200 Infinity Series, and is also compatible with major HPLC and UHPLC instruments from other manufacturers.

For streamlined workflows, it can be paired with AdvanceBio buffers and sample preparation kits available from Agilent. The rugged design ensures extended lifetime and consistent results, even with complex or challenging biological samples. The product is an excellent choice for researchers in pharmaceutical, biotechnology, and academic laboratories involved in protein characterization and analytical development projects.