Agilent, 793975-944, AdvanceBio RP-mAb Diphenyl, 4.6 x 150 mm, 3.5 µm

AdvanceBio RP-mAb Diphenyl, 4.6 x 150 mm, 3.5 µm. A reversed-phase diphenyl HPLC column with superficially porous particles and a wide (450 Å) pore size designed for mAbs and other larger proteins when alternate selectivity is needed or preferred.

Specifications:
Brand: AdvanceBio RP mAb Diphenyl
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 150 mm
Maximum Temperature: 90 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 3.5 µm
Particle Type: Superficially Porous
Phase: Diphenyl
Pore Size: 450 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-8

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The AdvanceBio RP-mAb Diphenyl column is an advanced reversed-phase chromatography solution engineered for the high-resolution analysis of monoclonal antibodies, antibody fragments, and related biomolecules. Featuring a 4.6 x 150 mm format with 3.5 micron particles, this column delivers robust performance with excellent peak shape and reproducibility across a wide range of protein sizes and complexities. Its unique diphenyl bonded phase offers enhanced selectivity and optimal retention for hydrophobic and aromatic analytes, enabling in-depth characterization of mAb charge variants, glycoforms, and protein aggregates.

Ideal for method development, quality control, and biopharmaceutical research, this column supports regulatory-compliant workflows in both R and D and manufacturing analytics. It is compatible with standard HPLC and UHPLC systems, and integrates seamlessly with Agilent 1260 Infinity II, 1290 Infinity II, and comparable third-party liquid chromatography platforms. The column functions optimally with Agilent AdvanceBio mobile phases and is complemented by a range of Agilent sample preparation solutions and detector modules. Designed for demanding laboratories, the AdvanceBio RP-mAb Diphenyl column delivers reliable results, batch-to-batch consistency, and extended column lifetime for the rigorous analysis of therapeutic antibodies and related proteins.