Agilent, 820750-921, AdvanceBio Oligonucleotide, 4.6 mm, fast guard

AdvanceBio Oligonucleotide, 4.6 mm, fast guard. Reversed-phase HPLC column designed for high-resolution IP-RP separation of oligos. Scalable chemistry platform supports analytical through prep purification for optimal resolution, yield, and purity.

Specifications:
Brand: AdvanceBio Oligonucleotide
Guard Column: Yes
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 5 mm
Maximum Temperature: 65 °C
Part Number Application: Oligos
Part Number Application Domain: Biopharma
Particle Size: 2.7 µm
Particle Type: Superficially Porous
Phase: HPH-C18
Pore Size: 120 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LC & LC/MS
UNSPSC Code: 41115711
pH Range: 3-11

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This specialized 4.6 mm fast guard column is designed to protect and extend the life of analytical columns used in advanced oligonucleotide separations. Engineered for high-efficiency performance, it effectively traps particulates and chemical contaminants, ensuring consistent chromatographic results and reducing downtime. Ideal for laboratories engaged in oligonucleotide analysis, the guard column is particularly beneficial during the purification and characterization of therapeutic oligonucleotides, such as antisense molecules, siRNA, and DNA or RNA aptamers.

Well-suited for cutting-edge biopharmaceutical and life science research, this accessory is recommended when working with complex biological samples or high-throughput workflows that require robust column protection. Optimized for compatibility with Agilent AdvanceBio Oligonucleotide columns, it integrates seamlessly into existing UHPLC and HPLC systems, including Agilent 1290 Infinity and 1260 Infinity II series. Researchers analyzing nucleic acid-based drugs, genetic assays, or quality control samples may expect enhanced reproducibility and sustained column performance. For streamlined operations and superior results in oligonucleotide workflows, users may also consider the broader AdvanceBio product portfolio, designed for advanced biomolecule characterization. This fast guard column represents a practical solution to maintain optimal system performance and data integrity in demanding laboratory environments.