Agilent, 820750-941, AdvanceBio Oligonucleotide, 4.6 mm, guard, 4µm

AdvanceBio Oligonucleotide, 4.6 mm, guard, 4µm. HPLC columns offer a high-quality, high-resolution IP-RP column chemistry platform that support analytical characterization through purification with method scale-up. The 4.6 mm, 4µm fast guard is a phased match guard to protect your column from matrix build-up.

Specifications:
Brand: AdvanceBio Oligonucleotide
Guard Column: No
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: HPLC
Length: 5 mm
Maximum Temperature: 65 °C
Particle Size: 4 µm
Particle Type: Superficially Porous
Phase: HPH-C18
Pore Size: 120 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LC & LC/MS
pH Range: 3-11

**********The following product description is generated by AI and is for reference only. If you have any questions, please contact customer service.**********
Designed for robust protection and optimal performance in oligonucleotide analysis, this guard column utilizes 4-micron particle technology, tailored for use with 4.6 mm ID columns. It securely connects upstream of analytical columns, effectively extending their lifetime by trapping particulates and strongly bound contaminants before they reach the main column bed. This component is ideal for supporting workflows in pharmaceutical characterization, synthetic oligonucleotide quality control, and nucleic acid research that rely on high-resolution, reproducible results.

The guard module is suitable for laboratories processing DNA and RNA therapeutics, antisense oligonucleotides, aptamers, and similar compounds, offering reliable sample preparation and cleanup. Its technology is optimized for use with reversed-phase high-performance liquid chromatography HPLC systems and pairs seamlessly with AdvanceBio Oligonucleotide analytical columns for cohesive performance. Compatible with a wide range of Agilent HPLC and UHPLC systems, the guard column ensures seamless integration, supporting streamlined method development and validation processes.

For best results, it is recommended to use this guard in conjunction with AdvanceBio Oligonucleotide columns and genuine Agilent hardware, ensuring consistent separations, instrument protection, and reproducible high-sensitivity detections in oligo-based workflow applications.