Agilent, GX96-101, AdvanceBio Gly-X InstantPC labeling module, 96-ct

AdvanceBio Gly-X InstantPC labeling module, 96-ct. Utilizes InstantPC dye to derivatize released glycans. The InstantPC dye delivers unmatched fluorescent brightness and MS signal, enabling a single labeling method to be deployed across different glycan analysis workflows. The small molecule size provides improved chromatographic peak resolution.

Specifications:
Application: Small molecule size for improved chromatographic peak resolution
Count: 96
Equipment & Reagents Provided by User: 96-well Thermocycler or two independent heat blocks, set for 90°C and 50°C. (e.g. Corning THERM-1001, 110V. THERM-1000, 230V). Note:Two GlykoPrep heaters, WS0271, can be fitted with VWR 13259-260 modular heating blocksVacuum pump (Millipore WP6211560, 110 V, WP6122050, 220V, Welch WOB-L Pump 2522). Note:If you have a vacuum manifold and pump other than the Millipore model suggested, please contact us for information. Alternative vacuum manifold may be used with a GX200 spacer in place of GX100 (see FAQs)
Label: InstantPC
Precision (well-to-well, day-to-day): <5% CV
Preservation of Sialylated Species: > 95 %
Protein Load Range: 1-40 µg
Recovery: > 95 %
Stability: Samples may be stored at -20°C for up to 6 months in Gly-X InstantPC eluent, or 4°C for up to 5 days in either Gly-X InstantPC eluent or after dilution with ACN/DMF
Technique: LC & LC/MS

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The AdvanceBio Gly-X InstantPC labeling module streamlines the preparation of N-glycans for fluorescence-based analysis in biopharmaceutical research and quality control environments. Designed for high-throughput laboratories, this 96-count kit enables rapid, efficient fluorescent labeling of released glycans with InstantPC dye, significantly enhancing sensitivity for downstream applications such as UPLC, LC-MS, and CE-based glycan profiling. The simplified workflow reduces hands-on time and minimizes sample loss, supporting both routine lot release testing and advanced glycosylation studies.

This module is ideal for glycan analysis of monoclonal antibodies, therapeutic proteins, and other glycoproteins, ensuring reliable quantitation and structural characterization. It delivers consistent results compatible with Agilent AdvanceBio LC columns, high-sensitivity detectors, and mass spectrometry platforms. The kit integrates seamlessly into automated sample preparation systems and is supported by Agilent’s method development tools and data analysis software for streamlined reporting and regulatory compliance. AdvanceBio Gly-X labeling technology is widely used in research, biosimilar development, and process monitoring, making it a versatile solution for laboratories focused on accurate glycan profiling and biotherapeutic characterization. For increased throughput, pair this module with Agilent 96-well plate automation and sample handling accessories.