Agilent, PL1812-2102, PLRP-S 1000Å, 100 x 300 mm, 10 µm

PLRP-S 1000Å, 100 x 300 mm, 10 µm. Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Hardware: SS
Inner Diameter (ID): 100 mm
LC Platform: Preparative HPLC
Length: 300 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisOligosPeptides
Particle Size: 10 µm
Particle Type: Fully Porous
Phase: PLRP-S
Pore Size: 1000 Å
Pressure Rating: 207 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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Agilent’s PLRP-S 1000Å, 100 x 300 mm, 10 µm preparative column is engineered for robust reversed-phase chromatography of large biomolecules. The rigid polymeric matrix with 1000 Å pore size and 10 micrometer particle size ensures efficient separation of proteins, peptides, and other macromolecules, even under challenging conditions such as high pH or the presence of aggressive organic solvents. This column is highly suitable for biomolecule purification workflows in fields such as biopharmaceutical research, protein characterization, and analytical biotechnology.

Typical applications include the purification and fractionation of recombinant proteins, mAbs, and other high molecular weight compounds from complex mixtures, supporting downstream process development and quality control. The column’s wide pore facilitates the separation of molecules with high molecular weights without significant diffusion limitations.

Compatible with a wide range of preparative HPLC systems, the PLRP-S format fits most standard preparative LC setups from Agilent and other major manufacturers. It is ideally paired with Agilent’s bio-inert HPLC instruments and accessories, and can be used in combination with other PLRP-S columns of different pore sizes or dimensions to achieve tailored purification strategies. Complete documentation and recommended operational guidelines are available for optimal performance and reproducibility.