Agilent, PL1812-2103, PLRP-S 4000Å, 100 x 300 mm, 10 µm

PLRP-S 4000Å, 100 x 300 mm, 10 µm. Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Hardware: SS
Inner Diameter (ID): 100 mm
LC Platform: Preparative HPLC
Length: 300 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisOligosPeptides
Particle Size: 10 µm
Particle Type: Fully Porous
Phase: PLRP-S
Pore Size: 4000 Å
Pressure Rating: 207 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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Agilent’s PLRP-S 4000Å, 100 x 300 mm, 10 µm is a polymeric reversed-phase chromatography column designed for the robust separation and purification of biomolecules, including large proteins and synthetic polymers. Engineered with a wide 4000Å pore size and durable polystyrene-divinylbenzene matrix, this column is ideal for handling high molecular weight analytes that require enhanced mass transfer and minimal size exclusion effects. Its 10 µm particle size balances column efficiency with low backpressure, making it suitable for both analytical and preparative scale separation in biopharmaceutical, proteomics, and polymer research laboratories.

This column supports a broad pH range and is chemically stable, allowing for diverse mobile phase conditions and repeated cleaning cycles, ensuring longevity and reliable performance. It is commonly utilized for the purification of antibodies, enzymes, nucleic acids, and synthetic polymers, as well as the characterization of protein aggregates. Compatible with most HPLC and process-scale LC systems, the column seamlessly integrates into Agilent chromatography platforms and can be paired with a range of PLRP-S columns with different pore sizes and dimensions to optimize purification workflows. Researchers benefit from its reproducibility, high loading capacity, and consistent lot-to-lot performance.