Agilent, PL1980-1201PK, AdvanceBio SEC 200A 1.9um 2.1x50mm PEEK

AdvanceBio SEC 200A 1.9um 2.1x50mm PEEK. A size exclusion column designed for higher resolution and faster separation of protein aggregates and fragments by UHPLC. PEEK-lined stainless steel hardware offers a metal-free sample flow path.

Specifications:
Brand: AdvanceBio SEC
Guard Column: No
Hardware: PEEK Lined SS
Inner Diameter (ID): 2.1 mm
LC Platform: BioInert
Length: 50 mm
Maximum Temperature: 80 °C (20 to 40 °C recommended)
Molecular Weight Lower Limit: 2000 Da
Molecular Weight Upper Limit: 700000 Da
Particle Size: 1.9 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 200 Å
Pressure Rating: 620 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: Phosphate Buffer/0.02% Sodium azide
Technique: LC & LC/MS
pH Range: 2-8.5

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The AdvanceBio SEC 200A 1.9um 2.1x50mm PEEK column delivers high-resolution size exclusion chromatography optimized for the characterization of biomolecules such as monoclonal antibodies, proteins, and aggregates. Featuring uniform 1.9 micron particle size and a 200 angstrom pore diameter, this column ensures sharp peak resolution and accurate molecular weight determination, making it highly suitable for both analytical and rapid screening workflows. Its PEEK hardware construction offers excellent chemical compatibility and minimizes metal-ion interactions, preserving the integrity of sensitive samples and extending column lifetime. Researchers benefit from enhanced reproducibility and low carryover, which is vital for quality control and regulatory compliance in biopharmaceutical development.

This column integrates seamlessly with both Agilent and other leading HPLC and UHPLC platforms, supporting workflows in protein therapeutics, biosimilar analysis, vaccine characterization, and stability studies. It is particularly well-suited for use alongside Agilent AdvanceBio SEC Guard columns to protect analytical columns and extend their performance. The compact 2.1 x 50 mm dimensions and efficient particle size enable high-throughput analysis with reduced solvent consumption. The AdvanceBio SEC 200A column ensures consistent and reliable results for laboratories focused on accurate and efficient molecular size characterization in complex biological samples.