Merck, 261556-5G, (L)-Dehydroascorbic acid

(L)-Dehydroascorbic acid (DHA) is a potent glycation agent that is produced by the oxidation of ascorbic acid (vitamin C). In vitro studies revealed that DHA is significantly more reactive than glucose and fructose in the glycation of lens proteins. Thus, DHA could be a critical precursor for the in vivo formation of advanced glycation end products (AGEs). DHA is a dimer when it is solid, but when it is dissolved in a solution, it becomes a monomer.