{"product_id":"abcam-ab102011","title":"Abcam, ab102011, Anti-RPL9 antibody","description":"\u003cp\u003eSize: 50µL\u003cbr\u003e\nRabbit Polyclonal RPL9 antibody. Suitable for IHC-P, WB, ICC\/IF and reacts with Mouse, Human, Zebrafish samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human RPL9 aa 1 to C-terminus.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Mouse, Human, Zebrafish,\u003cbr\u003e\nApplications:IHC-P, WB, ICC\/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Recombinant Fragment Protein within Human RPL9 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.P32969\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7Preservative: 0.01% Thimerosal (merthiolate)Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nThe RPL9 protein also known as Ribosomal Protein L9 plays a role in the structure and function of ribosomes. This protein is part of the large ribosomal subunit facilitating the assembly of proteins. With a molecular mass of approximately 21 kDa RPL9 resides in the cytoplasm where ribosomes are largely found reflecting its function. Broadly expressed across various tissues it is essential for ribosomal integrity and efficient protein synthesis.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nRPL9 is involved in ribosome biogenesis and translation processes. As a component of the ribosomal complex it aids in the production of new proteins by translating messenger RNA (mRNA) into polypeptides. This function is tightly regulated and essential for maintaining cellular protein homeostasis. Additionally RPL9 participates in ribosomal assembly ensuring the proper folding and function of ribosomes.\u003cbr\u003e\nPathways\u003cbr\u003e\nRPL9 plays an integral part in the mRNA translation pathway. It associates with other ribosomal proteins such as RPL5 and RPL11 forming a functional ribosomal unit. RPL9 contributes to the translation of mRNA into proteins an indispensable step in various cellular growth and proliferation pathways. Its interactions with these pathways highlight its role in regulating protein synthesis necessary for cell function.\u003cbr\u003e\nRPL9 has been linked to Diamond-Blackfan Anemia (DBA) and other ribosomopathies. These conditions arise from defects in ribosomal protein production leading to impaired hematopoiesis. RPL9 mutations could affect the assembly of ribosomes similar to other ribosomal proteins like RPS19. These diseases underline the importance of RPL9 in maintaining ribosome function and cellular health.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46854144524457,"sku":"ab102011","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab102011","provider":"Iright","version":"1.0","type":"link"}