{"product_id":"abcam-ab117129","title":"Abcam, ab117129, Methylated DNA Quantification Kit (Fluorometric)","description":"\u003cp\u003eSize: 48Test \/ 96Test\u003cbr\u003e\nDNA methylation is a covalent modification of the cytosine ring at the 5' position, resulting in 5-methylcytosine (5-mC).\u003cbr\u003e\nKey facts\u003cbr\u003e\nDetection method:Fluorescent,\u003cbr\u003e\nSample types:Saliva, Urine, Plasma, Tissue, Suspension cells, Adherent cells,\u003cbr\u003e\nAssay type:Quantitative,\u003cbr\u003e\nSensitivity:\u0026gt;= 50 pg\/well,\u003cbr\u003e\nAssay time:4h,\u003cbr\u003e\nAssay Platform:Microplate reader\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nDNA methylation is a covalent modification of the cytosine ring at the 5' position, resulting in 5-methylcytosine (5-mC). In somatic cells, 5-mC is found almost exclusively in the context of paired symmetrical methylation of the dinucleotide CpG. The biological important of 5-mC as a major epigenetic modification in phenotype and gene expression has been recognized widely. Quantification of 5-mC content or global methylation status in cells such as tumor cells could provide very useful information for detection and analysis of cancer.\u003cbr\u003e\nAbcam's Methylated DNA Quantification Kit (Fluorometric) (ab117129) is a complete set of optimized buffers and reagents to quantify global DNA methylation by specifically measuring levels of 5-methylcytosine (5-mC) in a microplate-based format.\u003cbr\u003e\nIt can be paired to use withHydroxymethylated DNA Quantification Kit (Fluorometric) (\u003cbr\u003e\nab117131\u003cbr\u003e\n), which specifically quantifies 5-hmC, for simultaneously quantification of both methylated and hydroxymethylated DNA.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions-Multi, Appropriate long-term storage conditions-Multi, Storage information-Please refer to protocols\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46843600011433,"sku":"ab117129","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab117129","provider":"Iright","version":"1.0","type":"link"}