{"product_id":"abcam-ab120864","title":"Abcam, ab120864, Nicotinamide, PARP inhibitor","description":"\u003cp\u003eSize: 100mg \/ 1g\u003cbr\u003e\nMW 122.13 g\/mol, Purity \u0026gt;99%. Amide form of vitamin B 3 . Plasma membrane and blood-brain barrier permeable. Precursor for β-nicotinamide adenine dinucleotide (NAD + ). Essential for the synthesis of NAD +  phosphate (NADP + ). Essential for energy metabolism, normal physiology and disease progression. Associated with a number of signaling pathways including oxidative stress, cell survival and inflammation. These effects are orchestrated partly through forkhead, Akt, Bad, caspase, MAPK and PARP signaling. Non-selective sirtuin inhibitor. Commonly used as 3D growth matrix components and additive for long-term growth.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:98-92-0,\u003cbr\u003e\nPurity:\u0026gt;99%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:122.13 g\/mol,\u003cbr\u003e\nMolecular formula:C6H6N2O,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to 100 mMSoluble in ethanol to 100 mM,\u003cbr\u003e\nBiological description:Amide form of vitamin B3. Plasma membrane and blood-brain barrier permeable. Precursor for β-nicotinamide adenine dinucleotide (NAD+). Essential for the synthesis of NAD+ phosphate (NADP+). Essential for energy metabolism, normal physiology and disease progression. Associated with a number of signaling pathways including oxidative stress, cell survival and inflammation. These effects are orchestrated partly through forkhead, Akt, Bad, caspase, MAPK and PARP signaling. Non-selective sirtuin inhibitor. Commonly used as 3D growth matrix components and additive for long-term growth.,\u003cbr\u003e\nIUPAC Name:Pyridine-3-carboxamide\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847421153449,"sku":"ab120864","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab120864","provider":"Iright","version":"1.0","type":"link"}