{"product_id":"abcam-ab123187","title":"Abcam, ab123187, Recombinant Human ECHDC1 protein","description":"\u003cp\u003eSize: 100µg\u003cbr\u003e\nRecombinant Human ECHDC1 protein is a Human Full Length protein, in the 1 to 307 aa range, expressed in Escherichia coli, with \u0026gt;95%, suitable for SDS-PAGE, Mass Spec.\u003cbr\u003e\nKey facts\u003cbr\u003e\nPurity:\u0026gt;95% SDS-PAGE,\u003cbr\u003e\nExpression system:Escherichia coli,\u003cbr\u003e\nTags:His tag N-Terminus,\u003cbr\u003e\nApplications:SDS-PAGE, Mass SpecSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nBiologically active:No,\u003cbr\u003e\nAccession:Q9NTX5,\u003cbr\u003e\nAnimal free:No,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nSpecies:Human,\u003cbr\u003e\nStorage buffer:pH: 7.4Constituents: PBS, 10% Glycerol (glycerin, glycerine)\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nECHDC1 also known as 'enoyl-CoA hydratase domain-containing protein 1' plays a role in fatty acid metabolism through its enzymatic activity. It weighs around 39 kDa and can be found in various tissues but it has higher expression levels in the heart and muscle tissues. This protein participates in metabolic processes by catalyzing the hydration of enoyl-CoA during the beta-oxidation of fatty acids.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nEVT-888 (another name for ECHDC1 used in some studies) acts as a component that affects metabolic pathways by mediating reactions associated with energy production. Though it is not actively considered formally as a part of large enzyme complexes ECHDC1 indirectly relates to mitochondrial function and energy regulation. It influences long-chain fatty acid breakdown assisting cells to maintain energy homeostasis.\u003cbr\u003e\nPathways\u003cbr\u003e\nECHDC1 influences key metabolic pathways like the beta-oxidation pathway of fatty acids and the mitochondrial respiration chain. This protein interacts closely with other proteins such as ACADVL (very long-chain specific acyl-CoA dehydrogenase) and HADHA (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha) playing a central role in energy conversion and mitochondrial efficiency.\u003cbr\u003e\nAlterations in ECHDC1 expression or function may associate with metabolic syndromes and cardiomyopathies due to its involvement in fatty acid metabolism and energy production. Disrupted interactions with metabolic proteins like HADHA and ACADVL can result in energy production deficits linking ECHDC1 to inherited metabolic disorders related to mitochondrial anomalies.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46844023210153,"sku":"ab123187","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab123187","provider":"Iright","version":"1.0","type":"link"}