{"product_id":"abcam-ab134945","title":"Abcam, ab134945, Anti-Syntaxin 16 antibody [EPR9156]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nRabbit Recombinant Monoclonal Syntaxin 16 antibody. Suitable for WB, ICC\/IF and reacts with Human samples. Cited in 4 publications.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR9156,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:WB, ICC\/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nSyntaxin 16 also known as STX16 is a member of the syntaxin family that has a central role in vesicular trafficking. This protein weighs approximately 37 kDa and is expressed in various tissues with notable presence in the brain and kidney. Syntaxin 16 is an integral membrane protein located mainly in the Golgi apparatus. It interacts with other SNARE proteins to mediate the fusion of vesicles with target membranes facilitating the movement of proteins and lipids within cells.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nSyntaxin 16 is involved in the proper distribution of proteins across cellular compartments. It is a component of the SNARE complex which is essential for membrane fusion events. Syntaxin 16 plays a significant role in endosomal trafficking where it helps in sorting and recycling of membrane proteins. The protein's function ensures that nutrients and signaling molecules are correctly transported and that cellular homeostasis is maintained.\u003cbr\u003e\nPathways\u003cbr\u003e\nSyntaxin 16 is involved in essential intracellular trafficking pathways. One such pathway is the endosomal-lysosomal pathway regulating the recycling and degradation of cellular components. It also plays a part in the transport between the trans-Golgi network and endosomes where it works closely with proteins like VAMP4 and Vti1a. These interactions ensure the directional flow of vesicles and the maintenance of cellular organization.\u003cbr\u003e\nSyntaxin 16 shows relevance to conditions affecting neurological and renal systems. Syntaxin 16 has been implicated in some neurodegenerative diseases suggesting disruptions in vesicular trafficking may contribute to pathogenesis. Furthermore altered expression or function of Syntaxin 16 affects renal function possibly connecting with proteins like VAMP2 which can influence kidney-related disorders. Understanding Syntaxin 16's role offers valuable insights into the cellular mechanisms underlying these diseases.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46844171288745,"sku":"ab134945","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab134945","provider":"Iright","version":"1.0","type":"link"}