{"product_id":"abcam-ab137046","title":"Abcam, ab137046, Anti-RPL26L1 antibody [EPR8478]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nRabbit Recombinant Monoclonal RPL26L1 antibody. Suitable for IHC-P, WB, ICC\/IF and reacts with Human, Mouse, Rat samples. Cited in 3 publications.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR8478,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:IHC-P, WB, ICC\/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nRPL26L1 also known as ribosomal protein L26-like 1 is a protein that functions in the translation process within cells. This protein has a mass of approximately 17.4 kDa and is part of the ribosomal machinery specifically associated with the 60S ribosomal subunit. Expression of RPL26L1 is found in tissues with high protein synthesis demand including the liver and testis indicating its role in protein production.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nRPL26L1 acts as a component of the ribosome contributing to protein biosynthesis by facilitating the assembly of ribosomes and ensuring the synchronized translation of mRNA into polypeptides. RPL26L1 participates in forming a ribonucleoprotein complex essential for maintaining the structural stability of ribosomes during translation. This function is critical for efficient cell growth and protein expression.\u003cbr\u003e\nPathways\u003cbr\u003e\nRibosome-associated activities see RPL26L1 play a significant part in the mRNA translation pathway. Involvement in the translation initiation process links RPL26L1 closely with other ribosomal proteins such as RPL26 which is involved in regulating mRNA translation initiation and elongation. Together these proteins ensure the fidelity and efficiency of protein synthesis connecting RPL26L1 to the foundational processes of gene expression.\u003cbr\u003e\nDisruptions in RPL26L1 function can relate to conditions such as Diamond-Blackfan anemia a rare genetic disorder linked to faulty ribosomal proteins. In this context RPL26L1 interaction with proteins like RPS19 reflects its role in the pathology of diseases that originate from ribosomal protein malfunctions. Maintaining appropriate RPL26L1 function is essential for ribosomal integrity and overall cellular health.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46850378105001,"sku":"ab137046","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab137046","provider":"Iright","version":"1.0","type":"link"}