{"product_id":"abcam-ab137065","title":"Abcam, ab137065, Anti-SLC45A3 antibody [EPR4795(2)]","description":"\u003cp\u003eSize: 100µL \/ 1mL\u003cbr\u003e\nAnti-SLC45A3 antibody [EPR4795(2)] (ab137065) is a rabbit monoclonal antibody detecting SLC45A3 in  Western Blot, IHC-P . Suitable for  Human . - Biophysical QC for unrivalled batch-batch consistency\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR4795(2),\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:IHC-P, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nWhat is this antibody validated in?\u003cbr\u003e\nAnti-SLC45A3 antibody [EPR4795(2)] (ab137065) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human samples.\u003cbr\u003e\nWhat is the molecular weight of SLC45A3?\u003cbr\u003e\nAnti-SLC45A3 [EPR4795(2)] (ab137065) specifically detects a band for SLC45A3 (UniProt: Q96JT2) at a molecular weight of 59kDa.\u003cbr\u003e\nTrial sizes available!\u003cbr\u003e\nTest your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl.\u003cbr\u003e\nDiscover our selection of trial-size antibodies\u003cbr\u003e\nOther related products\u003cbr\u003e\nWe have a range of other formats of antibody clone [EPR4795(2)] also available for your convenience: ab137065, Carrier free -\u003cbr\u003e\nab242056\u003cbr\u003e\n, PE -\u003cbr\u003e\nab317904\u003cbr\u003e\n, APC -\u003cbr\u003e\nab317943\u003cbr\u003e\n, Alexa Fluor® 488 -\u003cbr\u003e\nab317984\u003cbr\u003e\n, Alexa Fluor® 594 -\u003cbr\u003e\nab318026\u003cbr\u003e\n, Alexa Fluor® 555 -\u003cbr\u003e\nab318068\u003cbr\u003e\n, Alexa Fluor® 647 -\u003cbr\u003e\nab318109\u003cbr\u003e\n, Alexa Fluor® 750 -\u003cbr\u003e\nab321108\u003cbr\u003e\nSpecies reactivity\u003cbr\u003e\nMouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.\u003cbr\u003e\nPlease\u003cbr\u003e\ncontact us\u003cbr\u003e\nfor more information.\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nSLC45A3 also known as Prostate Cancer Associated Transcript 6 (PCAT6) is a member of the solute carrier family that functions primarily as a transporter. This protein has a mass of approximately 51 kDa. It is primarily expressed in the prostate but also found in other tissues though at lower levels. SLC45A3 is involved in transporting certain solutes which is important for maintaining cellular homeostasis.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThis transporter plays a critical role in regulating pH and solute concentration within the cells. SLC45A3 does not appear to belong to a large protein complex but it interacts with elements of the intracellular environment that modulate its activity. Its solute transportation role affects a range of cellular processes impacting overall cell health and function.\u003cbr\u003e\nPathways\u003cbr\u003e\nSLC45A3 operates within the cellular homeostasis and metabolic pathways. It closely relates to the acid-base balance pathway ensuring that cells maintain optimal internal conditions. Additionally its function can link to the androgen receptor signaling pathway an important pathway in prostate tissue where it may interact indirectly with other transport proteins that assist in maintaining homeostatic balance.\u003cbr\u003e\nSLC45A3 is significantly connected to prostate cancer and may also have implications in other types of cancer. It associates with the androgen receptor which plays a major role in the progression of prostate cancer. Understanding the dynamics of SLC45A3 can help in comprehending its role in these diseases potentially offering targets for new therapeutic strategies.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46844165816489,"sku":"ab137065","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab137065","provider":"Iright","version":"1.0","type":"link"}