{"product_id":"abcam-ab142139","title":"Abcam, ab142139, RepSox, TGF-beta type 1 receptor inhibitor","description":"\u003cp\u003eSize: 5mg \/ 25mg\u003cbr\u003e\nMW 287.32 Da, Purity \u0026gt;98%. Selective TGF-β type 1 receptor and ALK5 autophosphorylation inhibitor (IC 50  = 4 nM for ALK5). Selective for ALK5 over a range of other kinases, including p38 MAPK, JNK1 and GSK3. Replaces  Sox2  for reprogramming iPSCs. Active  in vitro  and  in vivo.  Cell-permeable .  .\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:446859-33-2,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:287.32 Da,\u003cbr\u003e\nMolecular formula:C17H13N5,\u003cbr\u003e\nPubChem:449054,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nBiochemical name:RepSox,\u003cbr\u003e\nBiological description:Selective TGF-β type 1 receptor and ALK5 autophosphorylation inhibitor (IC50 = 4 nM for ALK5). Selective for ALK5 over a range of other kinases, including p38 MAPK, JNK1 and GSK3. Replaces Sox2 for reprogramming iPSCs. Active in vitro and in vivo. Cell-permeable.,\u003cbr\u003e\nCanonical smiles:CC1=NC(=CC=C1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4,\u003cbr\u003e\nInChi:InChI=1S\/C17H13N5\/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14\/h2-10H,1H3,(H,19,22),\u003cbr\u003e\nInChiKey:LBPKYPYHDKKRFS-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:2-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847418433705,"sku":"ab142139","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab142139","provider":"Iright","version":"1.0","type":"link"}