{"product_id":"abcam-ab144211","title":"Abcam, ab144211, Bisindolylmaleimide X hydrochloride (Ro 31-8425), PKC inhibitor","description":"\u003cp\u003eSize: 1mg \/ 5mg\u003cbr\u003e\nMW 461 Da, Purity \u0026gt;98%. Potent, cell-permeable, reversible, ATP-competitive, and selective PKC inhibitor (IC 50  = 15 nM, rat brain PKC). Blocks antigen driven, but not IL-2 induced, T-cell proliferation. Shows less potent apoptotic effects than Ro-31-8220 (ab120374).\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:131848-97-0,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nMolecular weight:461 Da,\u003cbr\u003e\nMolecular formula:C26H25ClN4O2,\u003cbr\u003e\nPubChem:11539879,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in ethanolSoluble in DMSO,\u003cbr\u003e\nBiochemical name:Bisindolylmaleimide X hydrochloride,\u003cbr\u003e\nBiological description:Potent, cell-permeable, reversible, ATP-competitive, and selective PKC inhibitor (IC50 = 15 nM, rat brain PKC). Blocks antigen driven, but not IL-2 induced, T-cell proliferation. Shows less potent apoptotic effects than Ro-31-8220 (ab120374).,\u003cbr\u003e\nCanonical smiles:CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C5CC(CCN5C6=CC=CC=C64)CN.Cl,\u003cbr\u003e\nInChi:InChI=1S\/C26H24N4O2.ClH\/c1-29-14-18(16-6-2-4-8-19(16)29)23-24(26(32)28-25(23)31)22-17-7-3-5-9-20(17)30-11-10-15(13-27)12-21(22)30;\/h2-9,14-15H,10-13,27H2,1H3,(H,28,31,32);1H,\u003cbr\u003e\nInChiKey:IMBOYWXMTUUYGZ-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:3-[8-(aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione;hydrochloride\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847457165481,"sku":"ab144211","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab144211","provider":"Iright","version":"1.0","type":"link"}