{"product_id":"abcam-ab144269","title":"Abcam, ab144269, Heptelidic acid (Koningic acid), GAPDH inhibitor","description":"\u003cp\u003eSize: 250µg \/ 1mg\u003cbr\u003e\nMW 280.32 Da, Purity \u0026gt;95%. Potent, selective, irreversible GAPDH inhibitor. Selective, competitive DNA polymerase inhibitor. Antibiotic agent. Potently inhibits ATP generation in the glycolytic pathway. Inhibits DNA polymerases β, λ and terminal deoxynucleotidyl transferase (TdT) in family X. Inhibits caspase- 3 induction (IC 50  = 40 μM). Shows antiapoptotic effects.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:57710-57-3,\u003cbr\u003e\nPurity:\u0026gt;95%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nSource:Trichoderma sp.,\u003cbr\u003e\nMolecular weight:280.32 Da,\u003cbr\u003e\nMolecular formula:C15H20O5,\u003cbr\u003e\nPubChem:10945834,\u003cbr\u003e\nNature:Native,\u003cbr\u003e\nSolubility:Soluble in DMSO (10 mg\/ml)Soluble in ethanol (1 mg\/ml)Soluble in methanol (1 mg\/ml)Soluble in water (1 mg\/ml),\u003cbr\u003e\nBiochemical name:Heptelidic acid,\u003cbr\u003e\nBiological description:Potent, selective, irreversible GAPDH inhibitor. Selective, competitive DNA polymerase inhibitor. Antibiotic agent. Potently inhibits ATP generation in the glycolytic pathway. Inhibits DNA polymerases β, λ and terminal deoxynucleotidyl transferase (TdT) in family X. Inhibits caspase- 3 induction (IC50 = 40 μM). Shows antiapoptotic effects.,\u003cbr\u003e\nCanonical smiles:CC(C)C1CCC2(CO2)C3C1C=C(COC3=O)C(=O)O,\u003cbr\u003e\nIsomeric smiles:CC(C)[C@H]1CC[C@@]2(CO2)[C@@H]3[C@@H]1C=C(COC3=O)C(=O)O,\u003cbr\u003e\nInChi:InChI=1S\/C15H20O5\/c1-8(2)10-3-4-15(7-20-15)12-11(10)5-9(13(16)17)6-19-14(12)18\/h5,8,10-12H,3-4,6-7H2,1-2H3,(H,16,17)\/t10-,11-,12-,15-\/m1\/s1,\u003cbr\u003e\nInChiKey:JESMSCGUTIEROV-RTWAVKEYSA-N,\u003cbr\u003e\nIUPAC Name:(5aS,6R,9S,9aS)-1-oxo-6-propan-2-ylspiro[3,5a,6,7,8,9a-hexahydro-2-benzoxepine-9,2'-oxirane]-4-carboxylic acid\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847404441769,"sku":"ab144269","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab144269","provider":"Iright","version":"1.0","type":"link"}