{"product_id":"abcam-ab144291","title":"Abcam, ab144291, Latrunculin B, actin polymerization inhibitor","description":"\u003cp\u003eSize: 1mg\u003cbr\u003e\nMW 395.5 Da, Purity \u0026gt;96%. Cell-permeable actin polymerization inhibitor. Forms a 1:1 complex with monomeric G-actin. Shows less potent growth inhibition effects on cancer cell lines than Latrunculin A, (ab144290) (IC 50  values are 7.1 and 4.8 μM for HCT116 and MDA-MB-435 cells respectively). Shows antiglaucoma effects  in vivo.  .\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:76343-94-7,\u003cbr\u003e\nPurity:\u0026gt;96%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nSource:Latrunculia magnifica,\u003cbr\u003e\nMolecular weight:395.5 Da,\u003cbr\u003e\nMolecular formula:C20H29NO5S,\u003cbr\u003e\nPubChem:6436219,\u003cbr\u003e\nNature:Native,\u003cbr\u003e\nSolubility:Soluble in DMSO (25 mg\/ml)Soluble in ethanol (25 mg\/ml),\u003cbr\u003e\nBiochemical name:latrunculin B,\u003cbr\u003e\nBiological description:Cell-permeable actin polymerization inhibitor. Forms a 1:1 complex with monomeric G-actin. Shows less potent growth inhibition effects on cancer cell lines than Latrunculin A, (ab144290) (IC50 values are 7.1 and 4.8 μM for HCT116 and MDA-MB-435 cells respectively). Shows antiglaucoma effects in vivo.,\u003cbr\u003e\nCanonical smiles:CC1CCC2CC(CC(O2)(C3CSC(=O)N3)O)OC(=O)C=C(CCC=C1)C,\u003cbr\u003e\nIsomeric smiles:C[C@H]\/1CC[C@@H]2C[C@H](C[C@@](O2)([C@@H]3CSC(=O)N3)O)OC(=O)\/C=C(\\CC\/C=C1)\/C,\u003cbr\u003e\nInChi:InChI=1S\/C20H29NO5S\/c1-13-5-3-4-6-14(2)9-18(22)25-16-10-15(8-7-13)26-20(24,11-16)17-12-27-19(23)21-17\/h3,5,9,13,15-17,24H,4,6-8,10-12H2,1-2H3,(H,21,23)\/b5-3-,14-9-\/t13-,15-,16-,17+,20-\/m1\/s1,\u003cbr\u003e\nInChiKey:NSHPHXHGRHSMIK-JRIKCGFMSA-N,\u003cbr\u003e\nIUPAC Name:(4R)-4-[(1R,4Z,8Z,10S,13R,15R)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-1,3-thiazolidin-2-one\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847396610217,"sku":"ab144291","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/abcam-ab144291","provider":"Iright","version":"1.0","type":"link"}